STILLMEADOW, Inc. – Drug Development, Toxicology, Animal Health
Aquatic Toxicity
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Aquatic Toxicity
STILLMEADOW, Inc. conducts a variety of aquatic toxicity tests for both freshwater and saltwater project requirements. We provide GLP-compliant environmental services designed to meet the regulations of government and other agencies under EPA, OCSPP, and OECD guidelines.
Culture Facility
- Extensive facility focused on managing regimented production of commonly used test organisms.
- Tests designed based on guidelines and client-specific requirements.
Testing
- Performed in environmentally controlled chambers to ensure accuracy and reliability.
- STILLMEADOW, Inc. is dedicated to providing high-quality, regulatory-compliant testing services to meet the diverse needs of our clients.
Freshwater and saltwater organisms are exposed to a series of five test concentrations in a static and static-renewal test system in order to gather toxicity data for assessment of potential environmental hazards of the product to aquatic life. The following tests are the most common requested and can be customized to meet a client’s specific needs:
Daphnia spp. Static 48-hr Acute Toxicity Test (OCSPP 850.1010, OECD 202)
- Daphnia spp. Static 21-day Chronic Toxicity Test (OCSPP 850.1300, OECD 211)
- Static 96-hr. Fish Acute Toxicity Test (OCSPP 850.1075, OECD 203)
- Mysidopsis bahia Static 96-hr Acute Toxicity Test (OCSPP 850.1035)
- Mysidopsis bahia Static 28-day Chronic Toxicity Test (OCSPP 850.1350)
- Early life stage static toxicity test (OCSPP 850.1400 or OECD 210)
- Freshwater fish testing, Tier 1, microbial pest control agent (MPCA) test (OCSPP 885.4200)
- Freshwater aquatic invertebrate testing, Tier 1, microbial control agent (MPCA) test (OCSPP 885.4240)
Microbial Pest Control Agent (MPCA) Tests
Freshwater or saltwater organisms are administered the active MPCA test substance through environmental and dietary (fish only) exposure. Additionally, sterile filtrate or heat-killed test substance control groups are used to quantify any potential toxicity un-related to the active substance. Typically, only a single limit dose is used, however, multiple concentrations can be utilized per sponsor’s unique requirements.
The above guideline-driven tests provide a general toxicological response picture and additional add-ons such as dose level verifications, histology, necropsy, additional water quality parameters, etc. can be used to complete a full assessment of the toxicity potential of a product.
Contact us to discuss an aquatic toxicity test design that meets your needs.
Frequently Asked Questions
Below are answers to some common questions about aquatic toxicity and its implications:
Aquatic toxicity refers to the harmful effects of substances on aquatic organisms, such as fish, algae, and other aquatic life. These effects can range from reduced reproduction and growth to outright mortality.
Aquatic ecosystems are vital for maintaining biodiversity and supporting human life. When pollutants disrupt these ecosystems by causing toxicity to aquatic organisms, it can lead to ecological imbalances, loss of biodiversity, and compromised water quality, which in turn affects human health and economic activities such as fishing and tourism.
Regulatory agencies around the world have established guidelines and regulations to limit the discharge of toxic substances into water bodies and protect aquatic ecosystems. Compliance with these regulations often requires industries to conduct toxicity testing and implement measures to reduce or eliminate harmful discharges.
Stillmeadow, Inc. combines scientific expertise, state-of-the-art facilities, and a commitment to environmental stewardship to deliver reliable and cost-effective solutions for assessing and mitigating aquatic toxicity. Our multidisciplinary team works closely with clients to tailor approaches that meet their specific needs and regulatory requirements.
Aquatic toxicity can be caused by various substances, including chemicals from industrial processes, agricultural runoff, oil spills, and even pharmaceuticals. These substances can enter water bodies through direct discharge, atmospheric deposition, or runoff from land.
Aquatic toxicity is typically assessed through laboratory tests using standard organisms such as fish, daphnia, and algae. These tests measure the effects of substances on the organisms’ survival, growth, reproduction, and behavior over specific exposure periods.
Stillmeadow, Inc. offers a range of products and services designed to help industries assess and mitigate their environmental impact, including aquatic toxicity testing, risk assessments, and consulting services. By partnering with us, companies can identify potential risks to aquatic ecosystems and implement sustainable solutions to protect them.
For more information about Stillmeadow, Inc.’s aquatic toxicity services and how we can help your organization address environmental challenges, please visit the rest of our website or contact us directly. Our team is here to assist you in safeguarding aquatic ecosystems for future generations.