STILLMEADOW, Inc. – Drug Development, Toxicology, Animal Health
Toxicology
- Home
- >
- Toxicology
Stillmeadow Toxicology
At STILLMEADOW, Inc., we specialize in toxicology research, testing, and reporting for mammals, birds, fish, reptiles, and insects. Our dedication to innovation and excellence provides fundamental data for evaluating products to inform both manufacturers and the public of potential hazards. Industries of significant economic and societal importance depend on safe use of effective chemicals for a multitude of useful and beneficial purposes.
We adhere to key legislation such as FIFRA and TSCA to protect people and the environment from harmful chemicals. The Federal Insecticide, Fungicide, and Rodenticide Act (FIFRA) ensures pesticide registration with the EPA, emphasizing environmental protection. The Toxic Substances Control Act (TSCA) regulates the introduction of new and existing chemicals, with acute and subchronic toxicity testing providing vital data for safety evaluation.
Industries rely on the safe use of effective chemicals for numerous beneficial applications. STILLMEADOW, Inc. is proud to offer essential toxicology services for premanufacture notification, pesticide registration, and safety recommendations for consumers and employees.
- Chemical Toxicology Testing: Our laboratory conducts many different types of toxicology testing for chemicals, in addition to the analytical testing required by the OCSPP 830 series of guidelines. Mammalian, avian, insect, and aquatic systems are just some of the species types we can work with for chemical toxicology testing.
- Environmental Toxicology: We conduct aquatic, biodegradation, insect, plant and earthworm (soil) studies. Our greenhouse and indoor growth chambers are capable of conducting plant studies with over 800 plants of 10 different species concurrently. Our Aquatic department can formulate salt or fresh water for testing or use natural seawater, all with either static or renewal systems. We have colonies of insects to use in testing or we can order specific insects for any type of study.
- Occupational Health and Safety: Our diverse facilities provide us the flexibility to support standard and specialty GLP compliant environmental science tests necessary for global product submission under EPA, OECD and FDA guidance, as well as environmental compliance-based testing set forth by NPDES permits.
- Consumer Product Safety: Considerable legislation (FIFRA, TSCA) has been developed to protect people and the environment from possible harmful effects of chemicals. The Federal Insecticide, Fungicide, Rodenticide Act first passed in 1947 established procedures for registering pesticides with the USDA. in 1972 a major revision transferred responsibility of pesticide regulation to the EPA and shifted the emphasis to protection of the environment. The Toxic Substances Control Act passed in 1976 regulates the introduction of new or already existing Chemicals. Acute and subchronic toxicity testing protocols provide fundamental data for evaluating products to inform both manufacturers and the public of potential hazards. Industries of significant economic and societal importance rely on safe use of effective chemicals for a multitude of useful and beneficial purposes. STILLMEADOW, Inc. takes pride in its ability to provide the toxicology services needed for premanufacture notification, registration of pesticides, labeling and safe handling recommendations for consumers and employees.
Mammalian Toxicology
Acute and subchronic toxicity testing provides fundamental data for evaluating products to inform both manufacturers and the public of potential hazards. Industries of significant economic and societal importance depend on safe use of effective chemicals for a multitude of useful and beneficial purposes.
Aquatic Toxicology
STILLMEADOW, Inc. provides comprehensive environmental toxicology services, ranging from routine NPDES permit related compliance bioassays to sophisticated, complex testing customized to client needs.
Environmental Toxicology
A list of the Enviromental Toxicology studies conducted at STILLMEADOW, Inc. is available.
Entomology
STILLMEADOW, Inc. offers a wide range of services for testing urban insect pests and insect pests of medical and veterinary importance in laboratory and field settings.
Avian Toxicology
STILLMEADOW conducts non-target ecological effects avian toxicology studies with microbials and biopesticides (885.4050), and conventional chemicals (850.2100) using both a terrestrial (bobwhite quail) and water fowl species (mallard duck).
Expertise: Our team of toxicologists and genomics specialists are leaders in the field, with extensive experience in systems toxicology and toxicogenomics.
- Cutting-Edge Technology: We utilize state-of-the-art instrumentation and methodologies to deliver accurate and reliable results. Our commitment to quality ensures that our clients receive actionable insights for informed decision-making.
- Customized Solutions: We understand that every project is unique. Our experts work closely with clients to develop customized toxicological testing and consulting solutions tailored to their specific needs and objectives.
- Publication and Research: Explore examples of published research where our systems toxicology approach has revealed novel insights into chemical toxicity. Our contributions to the scientific community demonstrate the value of adopting innovative methodologies for toxicological assessment.
Frequently Asked Questions
Toxicology is the study of the adverse effects of chemical, physical, or biological agents on living organisms. It encompasses the identification, characterization, and assessment of toxic substances and their mechanisms of action.
Toxicological assessments involve evaluating the toxicity of substances to determine their safety for human health and the environment. This typically includes studies on acute toxicity, chronic toxicity, carcinogenicity, genotoxicity, reproductive toxicity, and ecological effects.
Toxicological studies are typically conducted using in vitro (cell-based) and in vivo (animal-based) models. These studies assess the effects of substances on various biological endpoints, such as cell viability, organ function, and biochemical pathways.
Regulatory agencies, such as the Environmental Protection Agency (EPA) and the Food and Drug Administration (FDA), use toxicological data to establish safety standards, set exposure limits, and evaluate the risks associated with chemicals and products. This information informs regulatory decisions on product approval, labeling requirements, and environmental regulations.
Environmental toxicology involves evaluating the impact of contaminants on ecosystems, wildlife, and human health. Toxicologists assess environmental toxicity through field studies, laboratory experiments, and ecological risk assessments to determine the potential hazards and risks associated with environmental contaminants.
- Toxicants can be classified into several categories, including:
- Chemical toxicants: Synthetic or naturally occurring chemicals that have toxic effects on living organisms.
- Physical agents: Non-chemical factors such as radiation, temperature extremes, and mechanical stress that can cause harm.
- Biological agents: Microorganisms, toxins, and allergens that can induce toxicity in biological systems.
Acute toxicity refers to the adverse effects of a substance that occur shortly after exposure and usually involve a single or short-term exposure. Chronic toxicity, on the other hand, refers to the adverse effects that develop over a prolonged period of repeated exposure to a substance.
Ethical considerations in toxicological research include ensuring the humane treatment of animals in studies involving animal models, obtaining informed consent in human studies, protecting confidentiality and privacy, and conducting research in accordance with ethical guidelines and regulations.
Contact STILLMEADOW, Inc. today to learn more about our comprehensive solutions and how we can support your research, regulatory, and safety assessment initiatives. Let us empower you with excellent service, years of experience, and extensive testing options to move your product forward.